Flp-mediated recombination removed the FRT-flanked stop cassette. The floxed stop cassette remains intact and must be removed to achieve expression of the halorhodopsin from the halophilic bacterium Natronomas pharaonis modified with an N-terminal signal peptide and a C-terminal endoplasmic reticulum export sequence fused in-frame with an enhanced yellow fluorescent protein (eNpHR2-EYFP) under the control of the CAG promoter. (J:190172)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count