A loxP site was inserted upstream of exon 25 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 25 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:189897)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count