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The murine Lin28b cDNA was inserted into the HS 21/45-vav vector containing 3' and 5' Vav1-regulatory elements. The Vav1-regulatory elements target expression of Lin28b to hematopoietic tissues. Transgenic mRNA is expressed in the bone marrow, spleen and thymus. Three lines were made, C3, D4, and D10. (J:189197)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
