One loxP site was inserted in intron 2 while an FRT flanked PGK-neo selection cassette followed by a second loxP site was inserted in intron 3. Subsequent excision of the selection cassette left exon 3 flanked by loxP sites. (J:189577)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count