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A cDNA encoding the mouse F2rl1 was inserted in frame into the ATG start codon. An internal ribosomal entry sequence (IRES) followed by a nuclear localization signal and lacZ gene were introduced downstream of the F2rl1 gene. An FRT-flanked Neo cassette was positioned 5' of the F2rl1. Chimeric males derived from blastocyst injections of positive clones into C57BL/6 recipients were mated with C57BL/6 FLPe females to remove the neo gene. (J:189278)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
