A splice acceptor site, CAG promoter, floxed neo stop cassette human MYC cDNA, and an FRT flanked IRES sequence and human CD2 cDNA were knocked into intron 1 via homologous recombination. The human CD2 cDNA is a signaling-deficient truncated version. (J:188564)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count