Approximately 4.3 kb of DNA encoding the catalytic domain, spanning from partway through exon 12 to partway through of exon 15, was deleted, a stop codon and AscI site was generated in the middle of exon 12, and an IRES-tauGFP-pA ACNF cassette was inserted into the AscI site thus creating a null allele with GFP reporter. (J:235858)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count