Dnaaf3^b2b1739Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is a G to A substitution at coding nucleotide 710 in exon 7 of the cDNA (c.710G>A, NM_001033548). This changes the glycine residue to aspartic acid at position 237 of the encoded protein (p.G237D). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Dnaaf3b2b1739Clo, and may be present in stocks carrying this mutation.