A floxed neo cassette was inserted upstream of the exon 2. An additional loxP site was inserted downstream of the exon 2. Cre-mediated recombination removed the neo cassette and left exon 2 floxed. (J:188677)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count