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The promoter drives expression of the FLAG-tagged cDNA in cartilage. In line 2, the transgene inserted between exon 5 and 6, resulting in a 3 kb duplication. RT-PCR confirmed the absence of transgene expression in the central nervous system. Western blot analysis confirmed the absence of endogenous protein expression in the spinal cord. (J:187705)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
