A loxP site was inserted upstream of the exons encoding the RING finger domain and a loxP site and FRT flanked neo cassette were inserted downstream of these exons via homologous recombination. (J:186765)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count