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A targeting construct containing a cassette with the cre/ERT2 sequence followed by an IRES-YFP-polyA-neo fragment was injected into TVB2 ES cells. Homologous recombination intoduced the construct in frame with the ATG start codon of the Fgf10 exon 1. Chimeric animals were crossed to Flp-expressing mice to delete the neo selection cassette. It is a loss-of-function allele for Fgf10. (J:187831)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
