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This transgene consists of E2 coding fragment of HPV11 under control of the human Ubiquitin C promoter. Nine transgenic founder mice were obtained. Of these three representative lines were analyzed in more detail . Line 613 is a representative of all transgenic founders. All organs examined expressed the transgene at similar levels by RT-PCR. By western blot, protein product was expressed in the skin. A similar transcription pattern was observed in all transgenic founder lines studied. (J:130233)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
