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Pkhd1tm2Cjwa mice were crossed with Tg(Gdf9-cre)5092Coo mice to remove the LSL (loxP-STOP-loxP) cassette leaving a single loxP site in intron 2. Upon removal of the LSL, the gene is reactivated and the expressed protein carries two SV5-Pk epitope tags on its extreme N-terminus. Northern blot analysis reveals the presence of 13 kb, 9 kb, 7.7kb and 7.5kb products identical in length to products generated from the wild-type allele. (J:187735)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
