Dnah11^b2b1289Clo

This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. The molecular lesion is an A to G substitution at coding nucleotide position 5632 in exon 33 of the cDNA (c.5632A>G, NM_010060). This changes the threonine residue to alanine at position 1878 of the encoded protein (p.T1878A). (J:175213) Additional incidental mutations were detected in sequencing for the causative mutation, Dnah11b2b1289Clo, and may be present in stocks carrying this mutation.