A neo cassette flanked by loxP and FRT sites was inserted upstream of exon 7. An additional loxP site was inserted downstream of exon 7. Flp-mediated recombination removed the neo cassette and left exon 7 floxed. (J:186742)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count