Insertion of a neo cassette via homologous recombination disrupted exon 6. RT-PCR and western blot analysis confirmed the absence of mRNA and protein expression in tissues from homozygous mice. (J:187109)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count