Cre recombinase was inserted into intron 14 of the Etl4 (Skt) locus by recombinase mediated cassette exchange using an exchangeable gene trap system using left element/right element (LE/RE) mutant lox sites. The IRES-cre sequence was exchanged with the IRES-lacZ-neo unit in the original trap vector by co-electroporation of the vector and pCAGGS-cre into TT2 ES cells containing the trapped Etl4 gene. (J:187217)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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