Exon 4, encoding the major transactivation domain, was flanked by LoxP sites and Ires-lacZ-neo flanked by FRT sites. Flp-mediated recombination removed the neo cassette. (personal communication)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count