A PGK-cre recombinase transgene, followed by a FRT site-flanked neomycin resistance cassette, was inserted into intron 1-2 of the ROSA26 locus. The construct was electroporated into Bruce4 ES cells. Chimeras were backcrossed to C57BL/6J mice and the line was maintained on the B6 background. (J:197875)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
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10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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