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The coding sequence of cre recombinase was divided into 2 parts. Each fragment was fused with GCN4-coiled coil domain, which allows stable dimers to form. Each Cre fragment is placed under the control of a Crym promoter in BAC RP24-62I5. The assembly of a functional Cre recombinase molecule can occur in cells where both promoters are active. The resulting modified BAC (BX1076) was used to generate this transgene. (J:100256)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
