A loxP site and FRT flanked neo cassette were inserted into intron 7 and a loxP site was inserted into intron 8 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 8 floxed. (J:186780)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count