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A construct with a 2.4 kb fragment of the Crx gene containing the promoter and proximal regulatory region driving cre cDNA followed by an SV40 polyadenylation sequence. The construct was generated from a plasmid that contained the Crx-Atoh7-IRES-cre sequence by excising the Atoh7 and IRES pieces. The purified Crx-cre transgene was injected into oocytes. 2 founders and 2 lines were obtained, crossed to GFP reporter mice, and analyzed for GFP and cre production. A representative line, 352, was analyzed in detail. (J:186563)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
