The transgene contained a 2 kb segment of human cosmid p18A4 (known as Clone B; abbreviated here as p18A4.B). Line 1352 contains 3 copies of the transgene that insert into intron 3 and result in a 70 kb deletion within intron 3. Western blot analysis confirmed ectopic expression in melanoma tumors. (J:11894, J:83183)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
--
Insertion, Intragenic deletion
Semidominant
1
4
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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