The mouse Ly6a promoter drives expression of the human MALT1 gene in the hematopoietic stem/progenitor cell compartment. Three lines (86A, 86B, 86C) were generated with 2 - 4 copies of the transgene inserted. RT-PCR and western blot analysis confirmed that transgene expression is restricted to Sca1+Lin- cells. (J:185590)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count