A loxP site was inserted 600 bp 5' of the transcription start site and a loxP site and FRT flanked neo cassette were inserted in intron 1 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:185955)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count