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The full-length human laminin alpha5 (LA5; LAMA5) cDNA with a bovine growth hormone polyadenylation signal was placed under control of the tetracycline resistance-operon tetO (7 copies) and the CMV minimal promoter. The construct was microinjected into single-celled C57BL/6NTac embryos. 15 potential founders were obtained. 2 expressed the transgene in the expected pattern, and one of these was analyzed further. (J:185850)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
