A targeting construct was generated by homologous recombination in a BAC containing the Neurog2 gene. An ERT2iCreERT2 sequence (icre/ERT2*; codon inproved cre fused in-frame N- and C-terminally with mutated human estrogen receptors) was inserted into exon 2 of Neurog2, replacing the entire coding sequence. The construct was electroporated into ES cells for homologous recombination. (J:185504)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6J x 129S4/SvJae)F1
Targeted
Insertion, Intragenic deletion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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