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A targeting vector containing a human beta-actin promoter-driven selection cassette consisting of a FRT site, lacZ sequence, the first loxP site, human beta-actin promoter driving the neomycin resistance gene, SV40 polyA, FRT site and a second loxP site was inserted downstream of exon 6 of the targeted gene, and another loxP site was inserted upstream of exon 6. Flp-mediated recombination removed the lacZ and neo cassette and left exon 6 floxed. (J:155845, J:193625)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
