Zinc finger endonuclease mediated homologous recombination inserted three silent mutations into the wild-type allele (one at the third position of codon 18 and two in the upstream of the two endonuclease binding sites, one of which also abrogates the ApaLI restriction site present in both Rab38cht and the normal wild-type allele). (J:185512)
Basic Information
(FVB/NCrl x C57BL/6J-Rab38cht)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count