Zinc finger endonuclease mediated homologous recombination inserted three silent mutations into the wild-type allele (one at the third position of codon 18 and two in the upstream of the two endonuclease binding sites, one of which also abrogates the ApaLI restriction site present in both Rab38cht and the normal wild-type allele). (J:185512)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(FVB/NCrl x C57BL/6J-Rab38cht)F1
Endonuclease-mediated
Nucleotide substitutions
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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