A neomycin resistance gene cassette, the kidney-specific cadherin promoter and the human beta-globin minimal promoter were inserted between the endogenous somatic promoter and exon 1. This insertion blocks the function of the endogenous somatic promoter and results in expression only in the kidneys. (J:185888)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count