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This transgene consists of a 152 kb bacterial artificial chromosome clone, 189N3, containing the whole mouse Dyrk1a gene with a 6 kb flanking fragment on the 5' side and a 19 kb flanking fragment on the 3' side and retrofitted to containa a PGKneo cassette (189N3 BAC clone from Research Genetics). The clone contains only the Dyrk1a gene and this transgene contains one extra copy of Dyrk1a. (J:182294)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
