The targeting vector was designed to insert a loxP site 16 bp before the start codon in exon 1 and a loxP-flanked neomycin cassette in intron 1. Cre-mediated recombination removed the floxed neo cassette leaving exon 1 floxed. (J:230564)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count