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The first vector contains the human lysozyme promoter driving immune-specific expression of the tet-on effector transgene with the rtTA2S*M2 variant. A second vector contains the tetracycline responsive element driving the inducible expression of the human cDNA with an HA tag. Lines 632 and 662 were generated with five (Tg632) or two (Tg662) copies of the rtTA and comparable (six to eight) copies of the HA-ELAVL1 transgenes. (J:102638)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
