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A construct containing the Camk2a promoter, loxP site, human APP cDNA with the Sweden and London mutations (K670N, M671L and V717I), FRT site, IRES, loxP site, human MAPT cDNA with P301L and R406W mutations, FRT site and neo cassette was inserted into the locus. (J:180977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
