A loxP site was inserted upstream of exon 6 and a loxP site and FRT flanked mcl-neo cassette were inserted downstream of exon 9 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exons 6 - 9 floxed. (J:185208)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count