Nucleotides in exon 13 encoding tyrosine 265 codon were changed to encode cysteine and an FRT flanked neo cassette was inserted downstream of exon 13 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:183837)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129/Sv and C57BL/6
Targeted
Insertion, Nucleotide substitutions
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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