The endogenous coding sequence was replaced by cre/ERT2 and the FRT-flanked neomycin resistance cassette was recombined out through breeding to a transgenic mouse expressing germline FLP1 recombinase. (J:264138)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count