A loxP site was inserted upstream of the exon encoding the first extracellular domain. A floxed neo cassette was inserted downstream of the exon encoding the transmembrane domain. Cre-mediated recombination removed the neo cassette. (J:183615, J:209892)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count