A floxed PGK-neomycin cassette was inserted in intron 15 and a third loxP site was placed in intron 17. Cre expression resulted in mice in which either the floxed neo alone was removed leaving exons 16 and 17 flanked by loxP sites or in which the floxed neo and exons 16 and 17 were removed. (J:184432)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
1
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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