A targeting construct introduced a T2A sequence and a codon improved cre (icre) sequence with an Frt-flanked neo cassette into exon 3 of the Foxa2 locus. The neo was removed from the germline by Flp-e mediated excision. (J:184814)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count