A lox511 site, loxP site and FRT flanked neo cassette were inserted upstream of exon 11 and a loxP site, a splice acceptor site, IRES site, EGFP cassette, F3 flanked hygromycin cassette and lox2272 site were inserted downstream of exon 15. Flp mediated recombination removed the neo and hygromycin cassettes. Cre mediated recombination removed exons 11 - 15. (J:184012)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count