A loxP site was inserted in intron 18 and an FRT-loxP flanked neomycin cassette was inserted upstream of exon 15. Flp recombinase excised the selection caqssette leaving exons 15 to 18 flanked by loxP sites. Expression of cre recombinase then removed expns 15-18. (J:184591, J:184592)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion, Intragenic deletion
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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