A loxP-flanked neomycin resistance cassette (neo) was inserted 3' of the coding sequence of Hoxb3 and was subsequently deleted by transient Cre recombinase mediated recombination in the targeted ES cells, leaving a single loxP site downstream of Hoxb3. Presence of the loxP site does not affect expression of the gene. (J:83563)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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