A loxP site was introduced to intron 3 and FRT-neomycin-FRT-loxP sequences were added to intron 5 of the targeted gene. (J:184202)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count