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Nine arginine residues in exon 14 were replaced with lysine (R->K) in this knock-in strain. The targeting cassette carried a loxP-flanked R->K segment, FRT site, PGK-neomycin cassette, loxP site, and FRT site. Flp-mediated recombination removed the neo cassette. (J:184053)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
