A loxP site was inserted upstream of the sequence and an FRT flanked neo cassette and loxP site were inserted downstream of the sequence via homologous recombination. Cre mediated recombination removed the sequence and the neo cassette. RNA analysis confirmed the absence of expression in homozygous mice. Northern blot analysis confirmed expression of Vmp1. (J:183786)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
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--
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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