This transgene contains the heptameric tetracycline operator (tetO) and human cytomegalovirus (CMV) minimal promoter driving expression of the coding sequence for enhanced green fluorescent protein joined to nucleotides 1-360 of human vesicle-associated membrane protein 7 (VAMP7, also called TI-VAMP), which include the coding sequence for the 100-amino acid N-terminal "Longin domain," followed by the rabbit beta globin intron and polyadenylation signal. (J:82809, J:183528, J:183756)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count