A loxP site was inserted upstream of exon 3. A neo cassette with a 3' loxP site was inserted downstream of exon 3. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts and the brain. (J:183741)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count