A loxP site was inserted upstream of exon 6. An FRT-flanked neo cassette with a 3' loxP site were inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exons 6 through 8 floxed. (J:183709)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count